Implantable Microelectrodes

The μNeurode Series Implantable Microelectrodes represent a breakthrough in invasive neural interface technology. Born from two decades of pioneering research, these microelectrode arrays are engineered to overcome the core technical barriers of traditional neural interfaces, offering a high-performance, customizable alternative to legacy systems like the Utah Array. Designed for preclinical and translational research, μNeurode enables precise, long-term recording and stimulation of neural activity across small animals, large mammals, and non-human primates, empowering breakthroughs in brain-computer interfaces (BCIs), neurophysiology, and disease modeling.

Key Features

Versatile Design, Tailored to Research Needs

The μNeurode Series encompasses three specialized configurations to adapt to diverse experimental models:

* Cera-μNeurode

Ceramic-based arrays for robust performance in acute and chronic studies requiring high mechanical stability.

* Flex-μNeurode

Flexible polymer substrates that minimize tissue trauma, ideal for long-term implantation in dynamic neural environments.

* UltraFlex-μNeurode

Ultra-compliant designs engineered to conform to curved brain surfaces, reducing inflammatory responses in extended studies.

All variants offer customizable channel counts (16 to 128 channels) and electrode lengths (0.5–3 mm), with adjustable center-to-center spacing (≥300 μm) to target specific neural populations—from deep brain nuclei to cortical layers.

Superior Material Science & Performance

* Low-Impedance Contacts

Platinum-iridium composite electrodes (<100 kΩ @ 1 kHz) ensure high-fidelity recording of neural spikes and local field potentials (LFPs), outperforming traditional platinum or iridium contacts.

 

* Biocompatible Insulation

Parylene-C coating provides exceptional dielectric strength and tissue compatibility, supporting stable performance for months in vivo.

 

* Microscale Engineering

Sub-10 μm electrode tips and 60 μm base diameters enable precise targeting of individual neurons while minimizing tissue disruption—a critical advantage for studies in small animals like mice and rats.

Seamless Integration with Existing Workflows

μNeurode arrays are universally compatible with leading multi-channel electrophysiology systems, including Blackrock, Plexon, AlphaOmega, Intan, Ripple, and TDT. This plug-and-play functionality eliminates the need for proprietary hardware, ensuring easy integration into existing research setups.

Advantages

Breaking Barriers in Neural Interface Technology

Flexibility for Diverse Research Models

As the only microelectrode array to match and exceed the performance of the top, μNeurode overcomes decades of technological monopolies. Its proprietary manufacturing process delivers >90% spike detection efficiency across channels, ensuring reliable data capture even in complex neural circuits.

From small animals (mice, rats, rabbits) to large mammals (cats, dogs, pigs) and non-human primates (macaques), μNeurode scales to meet the demands of varied experimental designs. Its flexible and ultra-flexible variants are particularly valuable for studies requiring long-term implantation, where tissue compliance is critical to reducing gliosis.

Rapid Customization & Scalability

Proven Biocompatibility & Durability

Gmedisys’s in-house engineering team offers tailored solutions—from custom channel layouts to specialized electrode geometries—with rapid turnaround times. This agility ensures researchers can adapt the technology to unique hypotheses, accelerating experimental timelines.

Tested in thousands of preclinical procedures, μNeurode arrays demonstrate exceptional biostability, with minimal foreign body response. This reliability makes them ideal for chronic studies in neuroprosthetics, neurodegenerative disease modeling, and cognitive neuroscience.

Applications

μNeurode enables breakthroughs across critical research domains:

Invasive BCI Development: Decoding motor intention and controlling external devices with sub-millisecond latency.

Sensory Neuroscience: Investigating visual, auditory, tactile, and pain processing at the cellular level.

Higher Cognitive Function: Mapping neural circuits underlying memory, decision-making, and social behavior in non-human primates.

Cross-Brain Region Circuit Mapping: Unraveling connectivity between distant neural structures in models of brain disease.

Neuropharmacology: Evaluating drug effects on neural activity with unprecedented spatial and temporal resolution.

 

μNeurode isn’t just a tool—it’s a catalyst for discovery. Backed by GMedisys’s decades of expertise in neural engineering, these microelectrodes empower researchers to push the boundaries of what’s possible in neuroscience.

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