Liquid Chromatography Tandem Mass Spectrometer (LC-MS/MS)
Combining advanced liquid chromatography (LC) with tandem mass spectrometry (MS/MS), the Novisar Apply 55+ Liquid Chromatography Tandem Mass Spectrometer (LC-MS/MS) integrates innovative ion optics, anti-matrix technologies, and user-centric software to excel in demanding applications—from clinical diagnostics to food safety and environmental monitoring. Designed for both routine testing and high-throughput laboratories, the Novisar Apply 55+ redefines what’s possible in trace-level analysis, ensuring accuracy even in the most challenging samples.
Key Features
Exceptional Sensitivity for Trace Detection
At the heart of the Novisar Apply 55+ lies a suite of technologies optimized for ultra-high sensitivity:
High-pressure quadrupole ion focusing & transmission: This proprietary design maximizes ion transmission efficiency, ensuring even low-abundance analytes are detected with precision.
180° curved axial acceleration collision cell: Enhances collision efficiency while minimizing interference from neutral particles, a critical advantage for quantifying trace compounds (e.g., ppb to ppt levels) in complex mixtures.
These innovations make the system ideal for applications requiring detection of minute concentrations—such as residual pharmaceuticals in biological fluids or environmental contaminants in water.
Superior Matrix Tolerance for Complex Samples
Complex matrices (e.g., serum, soil extracts, food homogenates) often suppress ion formation, skewing results. The Novisar Apply 55+ addresses this with:
Dual orthogonal electrospray ionization (ESI) source: Boosts ion yield and drastically reduces matrix effects, ensuring consistent performance even in high-matrix samples like fatty tissues or wastewater.
Vacuum interface cone with heated reverse curtain gas: Prevents contamination from matrix components, maintaining system cleanliness and stability over extended runs—critical for laboratories processing large batches of samples.
Robust Stability for Reliable Results
Consistency is paramount in analytical chemistry, and the Novisar Apply 55+ delivers:
High-efficiency desolvation ion source & interface: Enhances the system’s tolerance to varying sample compositions, reducing drift and improving reproducibility.
RF frequency adaptive technology: Stabilizes the quadrupole’s radio frequency power supply, ensuring precise mass selection and consistent performance over long workflows—vital for method validation and regulatory compliance.
Streamlined Operations
One-click auto-tuning & mass calibration: Automates critical setup steps, reducing operator error and training time.
User-friendly control & analysis software: Simplifies method development, data processing, and report generation, making advanced MS/MS accessible to both expert analysts and lab technicians.
Advantages
Unmatched Sensitivity: Detects trace analytes (ppb to ppt) in complex matrices, outperforming conventional LC-MS/MS systems in challenging samples.
Matrix Resilience: Minimizes matrix effects and contamination, ensuring accurate results for biological fluids, environmental samples, and food matrices.
Operational Stability: Delivers consistent performance over extended runs, reducing rework and ensuring compliance with strict regulatory standards (e.g., FDA, EU regulations).
Ease of Use: Intuitive software and automated workflows lower the barrier to entry, making advanced MS/MS accessible to labs of all sizes.
Applications
Food Safety & Agriculture
Residue Testing: Quantifies sulfonamide antibiotics in pork and other meats at trace levels, ensuring compliance with global food safety standards (e.g., EU Maximum Residue Limits).
Contaminant Screening: Identifies pesticides, mycotoxins, and veterinary drugs in crops and livestock products, safeguarding public health.
Environmental Monitoring
Persistent Organic Pollutants (POPs): Analyzes perfluorinated compounds (PFOA, PFOS) in groundwater, surface water, soil, and biota (e.g., fish), supporting environmental risk assessment and remediation efforts.
Pollutant Tracking: Detects trace industrial chemicals in air and sediment, aiding in source identification and regulatory compliance.
Clinical Diagnostics & Biomedical Research
Biomarker Quantification: Accurately measures vitamin D levels in serum, supporting assessments of bone health, immune function, and metabolic disorders.
Drug Monitoring: Quantifies pharmaceuticals and their metabolites in biological fluids (e.g., plasma, urine) to optimize dosing regimens and study pharmacokinetics.
Pharmaceutical & Life Sciences
Quality Control: Ensures purity and potency of drug substances and formulations, with trace-level detection of impurities.
Metabolomics: Profiles small molecules in biological samples to identify disease biomarkers or study metabolic pathways.
Whether you’re testing complex biological matrices, screening food for contaminants, or monitoring environmental pollutants, Novisar Apply 55+ combines sensitivity, stability, and ease of use to transform your workflow.